Olive leaf extract is a natural supplement made from the leaves of the olive tree (Olea europaea), a plant widely recognized for its health-promoting properties. People living in the Mediterranean region have used olive leaves for centuries in traditional medicine, and modern science is now uncovering the reasons behind their long-standing reputation.
What Is Olive Leaf Extract?
Olive leaf extract is a concentrated form of the nutrients found in olive tree leaves. It is rich in powerful antioxidants, especially polyphenols like oleuropein and hydroxytyrosol, which are believed to be responsible for most of its health benefits. These compounds help protect the body’s cells from damage caused by free radicals- unstable molecules that can contribute to aging and disease.
Health Benefits
1. Supports Heart Health
1. Olive leaf extract is best known for its cardiovascular benefits. Research shows it may help lower blood pressure and improve cholesterol levels by reducing the buildup of LDL (bad) cholesterol in the arteries. This effect helps promote healthy blood flow and reduces the risk of heart disease.
A 2010 study in The Journal of Nutrition found that olive leaf extract (OLE), rich in oleuropein, improved cardiovascular, liver, and metabolic symptoms in rats fed a high-carb, high-fat diet. OLE reduced fat buildup, oxidative stress, and glucose intolerance, though it did not affect elevated blood pressure.
2. Helps Manage Blood Sugar
The antioxidants in olive leaf extract can help lower blood sugar and improve insulin sensitivity, making it a useful supplement for people with diabetes or those at risk of developing the condition. Some studies suggest it may help prevent type 2 diabetes by reducing insulin resistance.
A 2012 controlled clinical trial published in The Journal of Medicinal Food showed that 500 mg of olive leaf extract daily for 14 weeks significantly reduced HbA1c and fasting insulin in type 2 diabetes patients. Animal models confirmed reduced starch digestion and absorption, supporting its hypoglycemic effects.
3. Boosts Immune System
Olive leaf extract has strong antimicrobial properties, meaning it can help fight bacteria, viruses, and fungi. This makes it useful for supporting the immune system and protecting against infections such as colds, flu, and respiratory ailments.
A 2018 comparative study found that olive leaf extracts (OLEs), especially water-based ones, enhanced immune responses in healthy human cells. OLEs increased CD8+ and NK cells, elevated IFN-γ and nitric oxide levels, and maintained immune balance, suggesting potential for preventing chronic inflammation and supporting cardiovascular and anti-tumor functions.
4. Reduces Inflammation
Chronic inflammation is linked to many health problems, including arthritis, diabetes, and heart disease. Olive leaf extract contains compounds that help reduce inflammation in the body, supporting overall health and well-being.
A 2023 study demonstrated that olive leaf extract (OLE) and its components—oleacein and oleuropein-aglycone—exert strong anti-inflammatory and antioxidant effects in human cell models of aging and viral infections. They reduced cytokine levels, modulated oxidative stress markers, and downregulated SARS-CoV-2 entry proteins, suggesting potential in managing inflammaging and respiratory infections.
5. Supports Brain and Cognitive Health
The antioxidants in olive leaf extract may help protect the brain from age-related decline and support memory and cognitive function. Some research suggests it may help reduce the risk of diseases like Alzheimer’s and Parkinson’s.
A 2022 review highlighted the neuroprotective potential of olive leaf phenolic compounds—especially oleuropein, hydroxytyrosol, apigenin, and luteolin. These compounds demonstrated antioxidant, anti-inflammatory, and anti-amyloid effects, offering promising support in preventing or managing Alzheimer’s and Parkinson’s diseases, while also addressing metabolic syndrome and neuroinflammation linked to neurodegeneration.
6. Aids in Weight Management
Early studies, mostly in animals, suggest that olive leaf extract may help prevent weight gain and reduce body fat, likely by influencing how the body processes fats and sugars. More research is needed in humans to confirm these effects.
A 2025 clinical trial found that supplementing a low-calorie diet with olive leaf extract (250 mg/day) helped reduce oxidative stress in obese women. Over 8 weeks, participants taking the extract had lower levels of malondialdehyde (a marker of oxidative damage) compared to those on a diet alone. However, the extract did not significantly affect liver enzyme levels or total antioxidant capacity. The results suggest that olive leaf extract may enhance the benefits of calorie restriction in weight management by lowering oxidative stress in people with obesity.
7. Promotes Healthy Skin
Olive leaf extract’s anti-inflammatory and antioxidant properties can benefit the skin by helping to heal wounds, reduce signs of aging, and protect against environmental damage.
In the study “Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice“, oral administration of olive leaf extract and oleuropein significantly reduced UVB-induced skin thickening, preserved elasticity, and inhibited tumor growth by downregulating MMPs, VEGF, and COX-2 expression.
In another pilot study “Efficacy of Olive Leaf Extract-Containing Cream for Facial Rejuvenation” (J Cosmet Dermatol, 2020), 36 participants with photoaged skin applied OLE cream twice daily for 2 months. Results showed significant improvement in skin hydration, reduced transepidermal water loss, diminished wrinkles, and enhanced skin texture—confirming its anti-aging and rejuvenating effects.
Dosage of Olive Leaf Extract
The typical recommended dosage for olive leaf extract is 500 to 1,000 milligrams per day, usually divided into two or three doses.
It’s important to start with a lower dose and gradually increase it to see how your body responds. Always follow the instructions on the product label or consult a healthcare professional before starting any new supplement.
Olive leaf extract is available in several forms, including capsules, tablets, liquid tinctures, and teas. Some people also use fresh or dried olive leaves in cooking, although the extract is much more concentrated.
Side Effects and Safety
Olive leaf extract is generally considered safe for most people when taken at recommended doses. However, some individuals may experience mild side effects such as:
- Allergic reactions (especially in those sensitive to olive products)
- Stomach discomfort or nausea
- Headaches or fatigue (rare, but possible when starting supplementation)
Caution and Potential Drug Interactions
- Diabetes: Olive leaf extract may lower blood sugar levels, increasing the risk of hypoglycemia when combined with diabetes medications.
- Low Blood Pressure: The extract may amplify the effects of blood pressure-lowering drugs, potentially leading to hypotension.
Blood Thinners: It may interfere with blood clotting and enhance the effects of anticoagulant medications. - Pregnancy and Breastfeeding: Due to limited safety data, olive leaf extract is not recommended during pregnancy or while breastfeeding.
- General Drug Interactions: Olive leaf extract may interact with multiple medications, including those for blood pressure, blood sugar, and blood thinning.
- Medical Supervision Advised: Individuals with chronic health conditions or those taking prescription medications should consult a healthcare professional before use.
How to Use Olive Leaf Extract
Olive leaf extract can be incorporated into your wellness routine in several ways:
- Capsules or tablets: The most convenient and precise way to take a consistent dose.
- Liquid tinctures: Can be added to water or juice for easy consumption.
- Teas: Made by steeping dried olive leaves in hot water.
- Topical applications: Some skin creams and ointments contain olive leaf extract for its skin-healing properties.
Choosing a Quality Product
When selecting an olive leaf extract supplement, look for products made from good quality olive leaves and standardized to a specific percentage of oleuropein, the key active compound. This ensures potency, consistency, and effectiveness.
NaturMed Scientific offers high-quality olive leaf extract tailored to your formulation needs. Our extracts are carefully sourced, standardized, and tested to meet the highest purity and safety standards, making them ideal for use in dietary supplements, cosmetics, and functional foods.
Olive leaf extract is a versatile and well-tolerated natural supplement with a range of potential health benefits. Its antioxidant, anti-inflammatory, and antimicrobial properties make it a valuable addition to a wellness routine for many people. While generally safe, it’s important to use olive leaf extract responsibly, follow recommended dosages, and consult a healthcare professional if you have any concerns or existing health conditions. With its long history of traditional use and growing scientific support, olive leaf extract continues to be a popular choice for those seeking natural ways to support their health.
Disclaimer: The Statement has not been evaluated by the EFSA, KFDA or FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. While the information provided is based on credible references, we do not make any specific claims or guarantees. It is important to consult with your healthcare advisor for personalized advice and guidance related to your health.
Reference:
- Olive Leaf Extract Attenuates Cardiac, Hepatic, and Metabolic Changes in High Carbohydrate–, High Fat–Fed Rats
- Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats
- Olive Leaf Extracts Act as Modulators of the Human Immune Response
- Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells
- Protective effect of olive leaves phenolic compounds against neurodegenerative disorders: Promising alternative for Alzheimer and Parkinson diseases modulation
- Phenolic-rich extract of olive leaf with a hypocaloric diet alleviates oxidative stress in obese females: a randomized double-blind placebo clinical trial
- Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells
- Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice
- Efficacy of Olive Leaf Extract-Containing Cream for Facial Rejuvenation
- Olive Leaf Extract: Health Benefits, Uses, Dosage, and More
- Olive Leaf Extract for the Brain, Diet, Herpes, and More
- Olive leaf extract: Health benefits, dosage, and side effects
